SkinMedica Lytera™
SkinMedica Lytera™

SkinMedica® Lytera

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A simple and effective approach to skin brightening.
Authorized Physician Reseller

Lytera™ is a simple and effective approach to skin brightening. It is a unique brightening formula that addresses the appearance of dark spots. Lytera works beautifully for all skin types, contains highly effective antioxidants, and serves as a mild exfoliant. It is available without a prescription.

Effective in reducing the appearance of:

  • Age spots
  • Dark spots
  • Photoaging
  • Freckles
  • “Pregnancy mask”


Lytera™ is clinically tested.

When clinically tested, women who tried Lytera Skin Brightening Complex reported a high level of satisfaction. Lytera showed similar results to 4% hydroquinone in patients with moderate to severe discoloration. And, it helped to improve the evenness of skin and overall skin condition.

Significant improvements in facial discoloration could be seen in as early as four weeks with continued improvement over time.

More Information
  • Easy to use and apply
  • Non-prescription
  • Hydroquinone-free
  • Appropriate for all skin types

What makes Lytera unique?

Lytera is a novel, non-prescription, non-hydroquinone skin brightening product that minimizes the appearance of skin discoloration and dark spots. Clinical studies with Lytera have shown:

High patient satisfaction in a long-term efficacy and tolerability study

  • Improvements seen as soon as 4 weeks
  • Significant reduction after 12 weeks
  • Continuous reduction over 6 months

What skin type is appropriate for using Lytera?

Lytera is appropriate for all skin types.

When should I use Lytera in my daily skin care routine?

Lytera should be applied after cleansing and toning the skin and prior to applying moisturizer and sunscreen.

Can I use Lytera together with TNS Essential Serum®? Which product should be applied first?

Although no studies looking at safety or altered efficacy have been conducted with combination of use of both products, it may be beneficial to use Lytera in combination with TNS Essential Serum. We recommend applying TNS Essential Serum first, wait until it dries, then apply Lytera followed by appropriate moisturizer and sunscreen.

How often should I apply Lytera?

For best results, you should use Lytera twice-daily.

What can I expect from using Lytera?

Comprehensive clinical studies demonstrated the following results:

  • Improved evenness of skin tone
  • Improved overall appearance of the skin
  • Increased radiance and clarity of the skin
  • Lessened appearance of darker patches and discolorations

Can I use Lytera if I do not have visible skin discoloration, but only want to brighten my complexion?

Lytera is designed to improve clarity, evenness and overall appearance of the skin.

What type of spots does Lytera improve?

In clinical studies, Lytera was used on patients with mild to severe dark spots.

Where do you apply Lytera?

Lytera can be used on the face, neck, décolleté or other affected areas.

Should I use Lytera only as a spot treatment?

Lytera can be used on the entire face.

How long can I use Lytera?

You should use Lytera as long as you wish to improve the overall condition of your skin. Clinical studies showed improvement in the appearance of skin discoloration as early as 4 weeks with continuous improvement over 6 months.

What are the side effects?

In clinical studies, the side effects associated with Lytera were mild and included mild irritation, tingling and dryness.

How long will it take before I see results?

In clinical studies, improvements were seen in as early as 4 weeks.

How long should I wait before applying sunscreen?

Sunscreen can be applied after Lytera application.

How long will one bottle last?

If Lytera is applied only to the face, it will last approximately 60 days.

Can I use Lytera if I'm pregnant?

We do not recommend using Lytera while pregnant, lactating or planning on becoming pregnant.

Skin Type Acneic Skin, Aging Skin, Combination Skin, Dry Skin, Hyperpigmented , Normal Skin, Oily Skin, Sensitive Skin
Size 2.0 fl. Oz
Brand SkinMedica
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A skin care regimen is a woman's best friend. Get optimal results by following a few steps:

AM (Morning)

  1. Start fresh with a cleanser like SkinMedica Facial Cleanser.
  2. Apply Lytera Skin Brightening Complex to affected areas (face, neck, décolleté).
  3. Follow up with your favorite SkinMedica moisturizer and a sunscreen like our Daily Physical Defense™ SPF 30+ sunscreen to help prevent sun damage and dark spots from forming.

PM (Evening)

  1. Start fresh with a cleanser like SkinMedica Facial Cleanser.
  2. Apply Lytera Skin Brightening Complex to affected areas (face, neck, décolleté).
  3. Complete the process with a product containing retinoids like our Tri-Retinol Complex™ followed by your favorite SkinMedica moisturizer.


Caution: We do not recommend using Lytera if you are pregnant, lactating or planning to become pregnant.

Key Ingredients

Tetrahexyldecyl Ascorbate
A stable, lipid-soluble ester form of ascorbic acid (Vitamin C).

Vitamin B3 improves skin moisturization and helps to enhance the barrier function of the skin. Helps promote even looking skin tone.

Ethyl Linoleate
Essential fatty acid ester helps promote even looking skin tone and helps support barrier function.

Mimics the lipid content of skin and helps support the skin barrier and is skin’s first line of defense against water loss.

Lipid soluble Vitamin A helps smooth dry, thick and rough skin by enhancing exfoliation. Helps even skin tone.

Dunaliella Salina Extract
Natural colorless carotenoids of phytoene and phytofluene extracted from unicellular algae. Colorless carotenoids help quench free radicals and brighten the skin.

Helps to brighten the skin.

Skin brightening peptide.

Helps even skin tone and brighten skin.

Glycyrrhiza Glabra (Licorice) Root Extract
Natural extract, rich in glabridin, a highly effective antioxidant with excellent skin brightening qualities.


Water/Aqua/Eau, Niacinamide, Butylene Glycol, Tetrahexyldecyl Ascorbate, Polyacrylate-13,  Caprylic/Capric Triglyceride, Tetrapeptide-30, Hexylresorcinol, 4-Ethoxybenzaldehyde, Retinol, Glycyrrhiza Glabra (Licorice) Root Extract, Ethyl Linoleate, Dunaliella Salina Extract, Tocopherol, Squalane, Cetyl Ethylhexanoate, Glycerin, Polyisobutene, Polysorbate 20, Phytic Acid, Disodium EDTA, Ethylhexylglycerin, Potassium Sorbate, Phenoxyethanol

Frequently bought together

  1. SkinMedica Lytera™
  2. +
  3. TNS Essential Serum®
  4. +
  5. SkinMedica® Retinol Complex 0.5
Total price: $0.00